John Ray's shorter notes




Jul 15, 2024

Study finds women who regularly eat ultra-processed foods are more likely to develop lupus

The journal article:

Ultra-Processed Food Intake and Risk of Systemic Lupus Erythematosus among Women followed in the Nurses’ Health Study Cohorts

The link

https://acrjournals.onlinelibrary.wiley.com/authored-by/Oakes/Emily+G .

This study was impressive for the range of controls used and for the fact that the HRs, while low, were a little higher than in most diet studies. But it was again a study of tertiles only, suggesting that there was no overall significance. Lupus is in any case a rare disease (213 cases out of 204,175 in this study). So the study is NO warrant to avoid UPFs


Women who regularly eat ultra-processed foods (UPFs) have a higher risk of developing a debilitating autoimmune disease, a study has suggested.

In a trial, those who had a diet rich in these foods – which are packed with artificial sweeteners and preservatives – were 56 per cent more likely to contract lupus, which leads to joint pain, skin rashes and fatigue.

And those who regularly consumed artificially sweetened beverages and sugary foods also had a 45 per cent greater risk of developing the condition.

The study, by researchers at Harvard University in the US, also found there was no connection between obesity and lupus – which suggests that the artificial ingredients in UPFs are to blame.

UPFs – such as ready meals, ice cream and some frozen food – have previously been linked to a number of life-threatening diseases, including cancer, Alzheimer’s and heart disease.

Systematic lupus erythematosus is a long-term condition where the immune system mistakenly attacks healthy tissue in the body.

Studies have shown that roughly one in every 1,000 people in the UK has lupus – and 90 per cent of sufferers are female.

While its causes are not fully understood, it has previously been linked to viral infections, certain medications, sunlight and the menopause.

But the research from Harvard, published in the medical journal Arthritis Care And Research, suggests there could be a correlation between the disease and eating foods that contain artificial colourings, sweeteners and preservatives.

However Professor Gunter Kuhnle, of the University of Reading, warned the research may not be conclusive.

‘Ultra-processed food may be one of the risk factors [for lupus] but there are likely to be other factors as well that may be more important,’ he explained.

‘People with a high-fat and high-sugar intake are more likely to have other conditions.

‘They are already less healthy, and that may be one of the reasons why this group of women are developing lupus.’

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